In this GEN panel discussion, three experts in cell and gene therapy development will share lessons and strategies learned ...

The partnership further establishes a compatible process for potency batch release assays further enabling follow-on universal vaccines from the Centivax antibody and T-cell epitope focusing platform.

This partnership leverages Emery Pharma's expertise to develop an IND-enabling GLP compliant potency release assay for GMP batches of the Centivax pan-influenza universal vaccine clinical ...

Moreover, there was no assay of potency or purity at all until the 20th century when a crude assay in rabbits was devised; some of the lesions in recipients were probably bacterial abscesses and ...

In medicine, an assay may determine the presence of a particular substance and its concentration. An "immunoassay" may be conducted on a vaccine, to determine its effectiveness or potency in ...

Vaccine-induced neutralising potency and immunity often wanes over time, and suboptimal response to vaccination can lead to breakthrough infections, particularly in older (>60 years) or ...

The initial selection of assays was based on the detection of immune markers that best correlated with protection against SARS-CoV-2 infections in preclinical animal studies and early clinical trials.

The current potency assay for influenza vaccines is SRID, which was developed and introduced into use more than forty years ago (16). It takes a lot of effort and time to prepare and calibrate RAs and ...

Background: The current compendial assay for haemagglutinin antigen potency in influenza vaccine is the single radial immunodiffusion (SRID) which is time consuming and can lead to delays in release ...

These projects will allow us to further advance innovation in vaccine manufacturing, particularly around potency assays that are important for characterization of key quality aspects of vaccines ...