Share on Pinterest Ozempic, the active ingredient of which is semaglutide, can also reduce the risk of heart disease, according to research. Steve Christo – Corbis/Corbis via Getty Images ...

Is Semaglutide Safe for Weight Loss? Semaglutide has been shown to be effective for weight loss in several large studies. In a clinical trial published in the Journal of the ASEAN Federation of ...

The Food and Drug Administration (FDA) has accepted for review the New Drug Application (NDA) for a 25 mg oral formulation of semaglutide for chronic weight management in adults with obesity or ...

Using semaglutide injections, scientists were able to reverse life-threatening cases of liver disease in a new clinical trial published in The New England Journal of Medicine.

Semaglutide injections reversed some cases of MASH liver disease in clinical trials, reducing inflammation in 62.9% of patients and offering new hope for those with the life-threatening condition.

Semaglutide, widely used for diabetes and weight loss, shows strong potential in reversing fatty liver disease, offering hope for millions affected by MASH globally.

The semaglutide group achieved a weight loss of 10.5% at 72 weeks compared with 2% for adults receiving placebo (estimated difference, –8.5 percentage points; 95% CI, –9.6 to –7.4; P < .001).

Semaglutide is the active ingredient in the weight loss medication Wegovy and the diabetes drugs Ozempic and Rybelsus, which are sometimes taken off-label for weight loss.

Phase 3 Trial of Semaglutide in Metabolic Dysfunction–Associated Steatohepatitis. New England Journal of Medicine, 2025; DOI: 10.1056/NEJMoa2413258 ...

TAKEAWAY: The use of semaglutide was associated with an increased risk for NAION among patients with diabetes throughout the study (hazard ratio [HR], 2.22; 95% CI, 1.37-3.60).

In patients with diabetes, semaglutide use was associated with an increased risk for nonarteritic anterior ischemic optic neuropathy, according to a study published in JAMA Ophthalmology. As ...