This manuscript characterizes a mutated clone of RNA polymerase I in yeast, referred to as SuperPol, to understand the mechanisms of RNA polymerase I elongation and termination. The authors present ...

When RNA molecules are synthesized by cells—a critical process in the creation of proteins and other cellular functions—they ...

3Department of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama. 4O’Neal Comprehensive Cancer Center, The University of Alabama at Birmingham, Birmingham, Alabama. Search for ...

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart disease characterized by irregular rhythms and right ventricular dysplasia. Sequence variations in desmosomal ...

This study presents an important finding on the molecular mechanism for transduction of environmentally induced polyphenism. The evidence supporting the claims of the author is solid. This paper would ...

Hyperactivation of RNA polymerase I (Pol I) transcription of ribosomal RNA (rRNA ... Cells were fixed in 4% paraformaldehyde (10 min at room temperature), permeabilized with 0.3% Triton X-100 in PBS ...

Autoinducer-2 (AI-2) has a widely accepted role in bacterial intra- and interspecies communication. Little is known about the relationships between AI-2 and NEC. This study found that AI-2 levels in ...

To examine a cost-effective alternative, we used a method, which confines sequencing to the 3’-end of mRNA and produces just one fragment per transcript, resulting in a dramatic decrease in sequencing ...