This study employs bioinformatics analysis of publicly available RNA sequencing databases to elucidate the pivotal ... Finally, we verified the hub genes utilizing real-time fluorescence quantitative ...

This manuscript characterizes a mutated clone of RNA polymerase I in yeast, referred to as SuperPol, to understand the mechanisms of RNA polymerase I elongation and termination. The authors present ...

When RNA molecules are synthesized by cells—a critical process in the creation of proteins and other cellular functions—they ...

Oregon Health & Science University, in collaboration with Oregon State University, has discovered the structural organization and protein components of a lipid-transfer complex known as LPD-3.

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart disease characterized by irregular rhythms and right ventricular dysplasia. Sequence variations in desmosomal ...

As libraries grow in size, these savings can be substantial. Assuming 8 substrate concentrations per Michaelis–Menten curve and 3 replicates per measurement, characterizing a 1000-member library costs ...

A negative control was generated with the same methods, replacing the antiapoptotic gene with 3 STOP codons in the donor plasmids ... by PCR amplification with Phusion U Hot Start DNA polymerase ...