Pentoxifylline (PTX) inhibits IkB phosphorylation ... Cells that were PI-negative and Annexin-V-positive were considered in early apoptosis. Cells that were positive for both PI and Annexin-V were ...

Paclitaxel (PTX) has been used for treating various malignancies. It stabilizes polymerized microtubules and enhances microtubule assembly and thus, arrests the cell cycle and induces apoptosis ...

Mammalian hosts coordinate various cell death pathways as part of the immune defense system against pathogens including ...

Oxysterols are a class of molecules derived from cholesterol via oxidation or as byproducts of cholesterol synthesis. Despite ...

Furin is identified as the key enzyme responsible for cleaving the apelin precursor. Inhibiting this cleavage could serve as ...

Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice.

It feels like the Splinter Cell remake has been on its way for a while now, which isn't helped by the fact it's been over three years since we heard anything official about the game. From what we ...

Many cells in multicellular organisms are specialised. They have specific roles in the organism of which they are part. Their structure is adapted to their function. They are often grouped ...

Although neurons are considered the basic units of the brain and nervous system, they do not do all the work. Glia are a non-neuronal category of cells that do not transmit electrical signals but ...