Ines Ibañez-Tallon is revealing how an understudied region of the brain plays an outsized role in opioid and nicotine ...

which work by binding to opioid receptors throughout the central nervous system, in both the brain and spinal cord. Finding the right sodium channel target, however, took decades of research ...

The Trump administration has proposed terminating a $56 million annual grant program that distributes naloxone, also known by ...

Figure 1: Generation of mice deficient for Gr in the nervous system. Figure 2: Mice lacking Gr in the nervous system display symptoms characteristic of Cushing syndrome including reduced size ...

Peptides have emerged as a promising area of research in the quest to understand and possibly mitigate pain. With their multifaceted mechanisms and potential to target specific pathways, peptides ...

The body produces natural opioid substances which are drawn to receptors throughout the nervous system, sending signals through neurons that induce pain relief, pleasure, and more. Results showing ...

The U.S. Food and Drug Administration (FDA) has approved a new drug for the treatment of moderate-to-severe pain that is a ...

TRD205's core innovation lies in its precise inhibition of AT2R, a receptor whose abnormal ... source without engaging the central nervous system, thereby avoiding opioid-related risks such ...