Next door, Dr. Rajadhyaksha was studying mouse models of cocaine addiction ... system's complex network of chemicals and receptors. Just as opioids stimulate the brain's reward system to release ...

But buprenorphine’s strength as a treatment is also a weakness. Buprenorphine is an opioid. Like methadone, the tightly ...

A paper published this month in the journal Current Addiction Reports discusses the merits of intranasal medications that can ...

The body produces natural opioid substances which are drawn to receptors throughout the nervous ... can address social behavior deficits in ASD model mice," said Yukio Ago, a professor at ...

"Applying new insights into receptor function, our novel compound demonstrated pain-relieving effects in mouse models without major opioid-related side effects like respiratory depression ...

Neuropeptide S receptor antagonists have been previously ... not yet been tested for their abilities to reduce opioid-related behaviors. Our lab is exploring the use of these compounds in animal ...

Compared with other antidiabetic medications, semaglutide was linked to a significantly lower risk of opioid overdose in ...

"Applying new insights into receptor function, our novel compound demonstrated pain-relieving effects in mouse models without major opioid-related side effects like respiratory depression ...

Methadone is a full opioid agonist, binding to and activating opioid receptors while blocking the binding of other ... a process that can take weeks or months in animal models. “As soon as you infuse ...

“Applying new insights into receptor function, our novel compound demonstrated pain-relieving effects in mouse models without major opioid-related side effects like respiratory depression,” McLaughlin ...