The transcription factor of neuraminidase 3 (NEU3) of DEGs was verified by double ... which is verified by JAK2 inhibitor and NEU3 inhibitor. Conclusion EPO, as a proinflammatory factor, accelerates ...
Aromatase is an enzyme that converts testosterone to estradiol, a type of estrogen. One study found that taking an estrogen blocker called an aromatase inhibitor while on testosterone therapy reduced ...
Limitations in current antiviral treatments, including resistance to neuraminidase inhibitors, have driven interest in developing polymerase subunit inhibitors, such as baloxavir and the newly ...
State Key Laboratory of Natural Medicines and Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China Department of Medicinal Chemistry, School ...
State Key Laboratory of Natural Medicines and Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China Department of Medicinal Chemistry, School ...
These next-generation STAT6 inhibitors demonstrate excellent oral bioavailability, cell permeability, and metabolic stability, and do not target STAT6 for degradation. DeepCure expects to select a ...
Neuraminidase inhibition assay was performed using Neuraminidase Inhibitors Screening kit (Beyotime Biotechnology, Shanghai, China) according to manufacturer’s instructions. Briefly, NA and various ...
The complete molecular library of NCI's DTP was downloaded from the institute's website 2. The chemical structures were processed with Pipeline Pilot Student Edition (version 6.1.5, Accelrys, San ...
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