Caption A 3-D model of adeno-associated virus (AAV) capsid structure: AAV capsid sixty subunits assemble to generate the icosahedral symmetric virus capsid. The viral asymmetric unit of the capsid ...

The researchers now plan to incorporate their new tool into a drug development program, leading to early clinical trials.

Surprisingly, we also found that the interaction between capsid and NEC is not restricted ... the genome is packed into newly assembled virus capsids, i.e., icosahedral protein containers of ...