Scientists at Rady Children's Institute for Genomic Medicine, and the Department of Neurosciences and Pediatrics at the ...

Two common and potentially deadly heart diseases can be caused by mutations in the same gene. Surprisingly, though, these two ...

Three INDs cleared by US FDA for TYRA's proprietary precision small molecules - - TYRA-300 to be evaluated in three Phase 2 studies: SURF ...

Hepatitis C virus (HCV) infection remains a major global health burden, affecting millions worldwide and contributing significantly to hepatocellular carcinoma (HCC) development.

Hepatitis C virus (HCV) infection remains a major global health burden, affecting millions worldwide and contributing significantly to hepatocellular ...

Direct-acting antivirals (DAAs) have dramatically changed the landscape of chronic hepatitis C virus (HCV) treatment and ...

Hepatocellular carcinoma (HCC), the most common type of primary liver cancer, accounts for about 75–85% of all liver cancer cases. Immune checkpoint ...

Now, scientists have revealed that a newly discovered 'fat gene' could be to blame. Experts from the University of Cambridge say that a mutation to a gene called DENND1B reduces the ability ...

single-sample gene set enrichment analysis; AUC, area under the receiver operating curve; ROC, Receiver operating characteristic; TMB, tumor mutation burden; CNV, Copy number variation; HCC, ...

The β-catenin gene is commonly mutated in HCC (158). SIRT1 is negatively associated with β-catenin mutation in HCCs, demonstrating that SIRT1 may promote oncogenesis in cancers independent of ...