Researchers have identified two natural compounds, patulin and xestoquinol, as new inhibitors of the enzyme topoisomerase 1, a key element in the correct functioning of DNA. The finding ...

The importance of understanding DNA repair Our cells protect their DNA by constantly monitoring and repairing any damage. When DNA is damaged, internal signals activate within the cell to pinpoint ...

Could it be that one of only three known markers directly targeting the DNA does not exist outside the realm of microbes? Now, researchers led by Xiaoqi Feng at the Institute of Science and ...

Decatur Police said last month they were investigating what caused the damage to the marker but had not determined if it had been damaged intentionally or accidentally. Authorities said on Tuesday ...

A Decatur historical marker commemorating African American Heritage has been replaced after it was damaged last month. Trump administration removes Democratic members of credit union watchdog NATO ...

Could it be that one of only three known markers directly targeting the DNA does not exist outside the realm of microbes? Now, researchers led by Xiaoqi Feng at the Institute of Science and ...

Another form of DNA methylation, 6mA, was erroneously reported by other researchers in several organisms before its detection was traced to bacterial contamination.

This study investigated the hypothesis that the variability of changes in indirect markers of exercise-induced muscle damage (EIMD) would be explained by work performed and/or torque generated during ...

Even basic cell division can introduce damage. Repetitive segments can become tangled, and random hits can cause cracks in the DNA structure. Each time a cell copies the DNA blueprint, dozens of ...

We now show that αSyn is preferentially enriched within the nucleolus in melanoma, where it colocalizes with DNA damage markers and DSBs. Inducing DSBs specifically within nucleolar ribosomal DNA ...