Johnson & Johnson (J&J) has announced that its dual-acting IL-23 inhibitor Tremfya (guselkumab) has been approved by the European Commission (EC) to treat adults with ulcerative colitis (UC).

MATILDA Ahdrian had her rectum removed and her anus sewn shut to save her life – a major operation that’s been dubbed ‘Barbie Butt’. “I don’t have a bum hole anymore ...