Vectors typically fall into the categories of viral and nonviral. Viral vectors commonly used in cell and gene therapy include adenovirus, adeno-associated virus (AAV), lentivirus, and retrovirus, ...

All compounds are either investigational or being studied for (a) new use(s). Efficacy and safety have not been established. There is no guarantee that they will become commercially available for the ...

UCL leveraged ViroCell's expertise in lentiviral vector manufacturing for an innovative CAR T-cell therapy for the treatment of paediatric acute lymphoblastic leukaemia ViroCell Biologics ...

UCL leveraged ViroCell’s expertise in lentiviral vector manufacturing for an innovative CAR T-cell therapy for the treatment of paediatric acute lymphoblastic leukaemia LONDON & NEW YORK--(BUSINESS ...

They will also provide lentiviral vectors essential for clinical development. CAR-T therapies, which reprogramme a patient’s immune cells to attack cancer cells, have shown remarkable success in ...

The vectors and payloads come in many forms – the most developed being lentiviral vectors with DNA payloads that integrate into the host genome. Alternative methods include lipid-based nanoparticles ...

Researchers commonly employ lentiviruses to modify cells genetically. However, they must overcome several challenges when using these viruses in the laboratory or clinic. In this episode, Charlene ...

Leprechaun analyzes vectors such as lentivirus and exosomes, accommodating up to 16 samples concurrently. The Luni consumable efficiently captures and sizes 1–25 μL of the vector, subsequently ...

Glioblastoma multiforme (GBM), as one of the most common malignant brain tumors, was limited in its treatment effectiveness with current options. Its invasive and infiltrative features led to tumor ...

In addition, integration of the recombinant lentiviral construct into the host genome provides permanent expression, including the progeny of dividing neural precursors. In this review, we describe ...