The San Francisco 49ers are preparing for their Week 11 contest against the Seattle Seahawks on Sunday at Levi's Stadium in ...

The 49ers have rewarded cornerback Deommodore Lenoir with a new contract. Reported as a five-year, $92 million extension, ...

The San Francisco 49ers are teetering on the brink of potential disaster on the injury front as they prepare for their Week ...

Nick Bosa's hip is an issue. He missed his second practice in a row on Thursday with a hip pointer that he suffered last week ...

Mitch Wishnowsky (back) missed a second practice this week, and newly signed punter Pat O’Donnell worked with long snapper ...

The San Francisco 49ers have another important division game on Sunday, but they may have to play without two of their biggest stars.

This did not escape two of Mayfield's big media fans, Fox sideline reporter Erin Andrews and studio host Charissa Thompson.

The 49ers also signed running back Patrick Taylor Jr. to the practice squad and released running back KeShawn Vaughn. Taylor ...