Therefore there is an urgent need to search new compounds characterized by diverse chemical structures and mechanisms of action ... as antibacterial and antifungal agents is an interesting ...

He also pointed to growing concern over agricultural antifungal use. “A lot of the new drugs being developed don’t have a novel mechanism of action,” Beardsley said. And in many cases ...

"For decades, clinicians have relied on a handful of antifungal classes, with few mechanisms of action and significant limitations due to spectrum of activity, drug toxicities, or drug-drug ...

Discovering antifungals with novel mechanisms of action is essential in the fight against drug-resistant fungi, which pose a serious concern for public health. However, progress on new antifungals is ...

An often-overlooked mechanism of gene regulation may be involved in the failure of antifungal drugs in the ... used the known mode of action of fluorocytosine on A. fumigatus as the basis for ...

NovaBiotics’ platform technologies leverage defense strategies of the innate immune system and provide first-in-class antibacterial and antifungal ... platforms have mechanisms of action that ...

These methods have been adopted as part of the CLSI Reference Methods for Antifungal Susceptibility Testing. Strong support for these research efforts are drawn from different sources including the ...