Secondary analysis findings from the EMPACT-MI trial highlight empagliflozin's significant cardiovascular and kidney benefits when initiated soon after an acute myocardial infarction.

Understanding the alkaline stability of quaternary ammonium (QA) cations tethered to polymer backbones in anion-exchange membranes (AEMs) is crucial to advance the long-term performance of ...

Objective Type 2 diabetes mellitus and metabolic dysfunction-associated steatotic liver disease (diabetic MASLD) frequently coexist and worsen liver and non-liver outcomes, but effective ...

In this study, a structure-based drug discovery pipeline was implemented to identify novel PKMYT1 inhibitors with high binding stability and anticancer potential. Pharmacophore models were constructed ...

Structure-based drug design has played a key role in the development and characterization of isoform selective mammalian nitric oxide synthase (mNOS) inhibitors. (1, 2) NOS, an enzyme responsible in ...