Malignant peripheral nerve sheath tumors (MPNSTs) are a rare subtype of sarcomas arising from peripheral nerves, occurring either sporadically or in association with neurofibromatosis type 1 (NF1).

This term was first proposed by experts at the National Institutes of Health in the United States in 2016 to delineate neurofibromas that may undergo malignant transformation into malignant peripheral ...

1Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana. 7IU Simon Comprehensive Cancer Center, Indiana University School ...