Explore the impact of 3D models in drug discovery and how they enhance predictive insights in pre-clinical research.

Antibiotics are the cornerstones of modern medicine because they combat bacterial infections effectively. However, their use is not without risks, particularly concerning your kidney health. Your kidn ...

Understanding and categorizing the various types of tubulointerstitial responses in acute kidney injury (AKI) may lead to the ...

Potassium can lower blood pressure, even on a salty diet. Simulations showed that increasing potassium intake significantly ...

Guided by changes in steady-state expression levels of known FBW7 substrates in cystic tubules, we identified the SOX9-WNT4 axis as a crucial regulator of tubulointerstitial fibrosis and showed that ...

Common over-the-counter anti-inflammatory painkillers like ibuprofen and aspirin can damage the kidney tubules – tiny tubes in the kidneys that return filtered nutrients and fluids back to the ...

Common over-the-counter anti-inflammatory painkillers like ibuprofen and aspirin can damage the kidney tubules – tiny tubes in the kidneys that return filtered nutrients and fluids back to the blood.

The kidney is a central organ of the mammalian ... BRN1 commits cells to becoming cells of the Henle's loop and distal tubules. Irx genes, possibly together with BRN1, control the fate of the ...

Renal glycosuria is a much rarer form of glycosuria. This happens when your kidney’s renal tubules — the parts of the kidneys that act as filters in your urinary system — don’t filter ...

Introduction: Cisplatin-induced acute kidney injury (AKI) is primarily caused by oxidative stress from reactive oxygen species (ROS) accumulation. Developing ROS scavengers presents promising ...