This manuscript characterizes a mutated clone of RNA polymerase I in yeast, referred to as SuperPol, to understand the mechanisms of RNA polymerase I elongation and termination. The authors present ...

Northwestern Medicine scientists have uncovered how a testis-specific protein contributes to tumor growth and progression in ...

CDK9, a core component of positive transcription elongation factor b (p-TEFb) playing a crucial role in RNA polymerase II transcription (RNAP II) initiation to elongation, is a promising target for ...

miRNA biogenesis and dysregulation in LC The biogenesis of miRNAs is a complex process ... pathway involves transcription of miRNA genes by RNA polymerase II, followed by processing by enzymes ...

Water present at the interface of a protein–RNA complex plays a critical role in guiding its structure, stability, and function. Therefore, studying the microscopic properties of interfacial water is ...

The results will be of use to researchers in the field of germ cell/meiosis as well as RNA biosynthesis and chromatin. The present study revealed that zebrafish had spermatogonial stem cells (SSCs) ...