This manuscript characterizes a mutated clone of RNA polymerase I in yeast, referred to as SuperPol, to understand the mechanisms of RNA polymerase I elongation and termination. The authors present ...

The Mediator complex is a system that regulates protein-coding gene transcription, where mediator of RNA polymerase II transcription subunit 16 (MED16) is a subunit belonging to this system.

Three main types of RNA are involved in protein synthesis: mRNA, tRNA, and rRNA. mRNA is synthesized by the enzyme RNA polymerase ... transcription elongation factor P-TEFb protein complex.

Northwestern Medicine scientists have uncovered how a testis-specific protein contributes to tumor growth and progression in ...

Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact on cellular function and human disease.

We are also refining and applying ultrahigh-resolution spectroscopy techniques to dissect multistep complex biochemical processes ... Single-Molecule Nanoscopy Elucidates RNA Polymerase II ...