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Sponge pores can mimic microfluidics, placing cells and virus particles in close proximity to increase transduction ...
Lentiviral transduction is a popular and powerful gene delivery method for downstream applications such as cell line generation, therapeutic model generation and CAR-T research. However, current ...
Sponsored content brought to you by ATTCGA ➜ ATTCCA That’s gene editing. On paper, it is merely the rearrangement of letters. However, the road to editing genes in hopes of a therapeutic benefit is ...
In this study, lentiviral vector–transduced autologous CD34+ HSCT was successful in treating severe LAD-I. (Funded by Rocket Pharmaceuticals and the California Institute for Regenerative ...
Viral gene delivery is a ubiquitous laboratory technique with a myraid of uses. Understanding the basics of gene delivery workflows, from vector selection and cloning to transduction, is a fundamental ...
Hosted on MSN25d
A new strategy to enhance gene therapy for sickle cell diseaseTo improve the efficacy of gene therapy when using anti-sickling beta globin gene transfer, they added cyclosporin (CsH) to increase transduction by inhibiting lentiviral restriction factors.
Lentiviruses have the unique ability amongst retroviruses of being able to infect non-cycling cells. Vectors derived from lentiviruses have provided a huge advancement in technology and seemingly ...
Leprechaun analyzes vectors such as lentivirus and exosomes, accommodating up to 16 samples concurrently. The Luni consumable efficiently captures and sizes 1–25 μL of the vector, subsequently ...
Hosted on MSN1mon
CAR-M technology: A novel approach to overcome CAR-T limitations in solid tumor treatmentOptimizing transduction timing ... stable CAR expression in macrophages derived from peripheral blood using lentivirus." KRICT President Young-Kuk Lee emphasized, "This technology could complement ...
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