Researchers found that inhibiting GSK-3 led to less defects in the axonal transport process and less neuronal cell death, while inhibiting ERK1 led to more transport problems and more cell death.

This explainer outlines how neurons and glial cells coordinate electrical and chemical signals to form complex brain networks that govern thought, behavior, and consciousness. It also explores how ...

Immune system scientists and computational biologists are developing a new tool to investigate how the body fights disease.

University at Buffalo researchers shed some light on an enduring neuroscience mystery: How exactly does a mutated huntingtin ...

“To be a stem cell donor gives a patient with a blood disease like leukemia or other kinds of blood cancers a chance at curing their disease, a chance at life,” says Warren B ...

This paper investigates how isoform II of transcription factor RUNX2 promotes cell survival and proliferation in oral ... that was partially suppressed through RUNX2 regulation of PRDX2 expression.

The team created stem cells from these white blood cells, and due to their pluripotency, the cells developed into cerebral organoids somewhat similar to developing human brains. “The central ...

As we age, blood stem cells, the essential source of new blood cells in the body, can accumulate genetic mutations. These mutations can give the cells a growth advantage, laying the foundation for ...

With advances in genome sequencing, it has become apparent that tens of clones persist in the blood ... mature cells. Single-cell transcriptomics, an analysis of the RNA transcripts expressed ...

A landmark study 6 in 2021 offered an early comprehensive examination of the use of cell-free RNA to detect cancer. This revealed that identifying RNAs from highly expressed tumour genes improves ...

A new study has identified a novel strategy for treating acute myelogenous leukemia (AML), an aggressive blood ... gene expression programs that drive the phenomenon in leukemic stem cells.

School of Mechanical Engineering, and Jiangsu Key Laboratory for Design and Manufacture of Micro-Nano Biomedical Instruments, Southeast University, Nanjing 211189, China ...