Small-molecule irreversible tyrosine kinase inhibitors as high potent agents have led to improvements in disease-free and overall survival in patients with HER2-amplified cancer. The approved ...

Objectives To estimate the social costs of occupational asthma in the UK. Methods A desk-top approach using cost-of-illness methodology was employed, defining direct and indirect lifetime costs for ...

Young adults who experienced bronchiolitis in infancy may face irreversible airway obstruction, according to new research ...

A general phenomenological kinetic model of irreversible protein aggregation in aqueous solution proceeding via non-native conformations is examined with a view toward the development of techniques to ...