Single-cell imaging and mass spectrometry data reveal adenosine in the DNA of mammalian cells can be methylated by METTL3 to form N6-methyladenosine in response to DNA damage.

Similarly, the percentage of cells with 6mA foci was significantly increased in response to HU and gemcitabine, but not MMC (Figure 5D, E). To assess whether DNA damage levels were linked to the ...

The DNA of human cells consists of a sequence of about 3.1 billion building blocks. Cells go to great lengths to maintain the ...

A new study published in Life Science Alliance reveals a key genetic connection between cancer susceptibility and tissue ...

A medical breakthrough could result in the first treatment for rare but serious diseases in which genetic defects disrupt cellular energy production. Researchers have identified a molecule that helps ...

Gene editing and many other useful biotechnology tools came from studies of bacteria fighting off viral invaders. But ...

a period when the largest desert in the world temporarily turned into a humid savanna-like environment. By analyzing the DNA of two 7,000-year-old ...

DNA (deoxyribonucleic acid) is the nucleic acid polymer that forms the genetic code for a cell or virus. Most DNA molecules consist of two polymers (double-stranded) of four nucleotides that each ...

DNA nanostructures provide nanometer-precise control over molecular arrangement, allowing control of both ligand spacing and valency. Here, we produce a DNA nanostructure decorated with controlled ...

Professor Yimin Zou and colleagues have published surprising results that reveal that RYK expression inhibits wound healing, ...

Pancreatic cancer is a significant cause of cancer-related mortality and often presents with limited treatment options. Pancreatic tumors are also notorious for their immunosuppressive ...