experimental acquisition and data analyses approaches using electron microscopy and electron tomography based methods. This protocol describes the optimization of RNA preparation conditions for ...

Electron tomography images structures in three-dimensions, and with electron holography it is possible to map electric and magnetic potentials. Advances in optics and the implementation of high ...

Cryo-EM has made major strides in recent years, enabling high-resolution imaging of biological structures. Cryo-electron tomography (cryo-ET) builds on the core principles of cryo-EM, combining them ...

The BEMS Core Facility (MCDB Department) is an open access user facility that serves the University of Colorado, other non-profit institutions, as well as industry partners worldwide. We have three ...

The University of Colorado Boulder Biochemistry Department's Krios Electron Microscopy facility (BioKEM) offers single particle cryo-EM and cryo tomography of plunge-frozen samples. The BioKEM ...

Published today in Nature, the study describes how scientists used cryo-electron tomography, guided by fluorescence microscopy, to explore deep inside an Alzheimer's disease donor brain.