Every living cell must interpret its genetic code - a sequence of chemical letters that governs countless cellular functions.

Our cells' identity is shaped by DNA tags called methylation. New tech, scDEEP-mC, maps these tags in single cells with ...

Scientists at The Wistar Institute have discovered how a key protein from the Epstein-Barr virus (EBV), EBNA-LP, ...

Franklin W. Stahl, an American molecular biologist whose landmark 1957-58 experiment with colleague Matthew Meselson revealed ...

Drs Ursula A. Matulonis and Joyce F. Liu discuss targeting DNA damage and repair and replication stress in endometrial cancer.

MSK researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer.

Credit: Kateryna Kon/Science Photo Library/ What is DNA, and how does it work? You don't need a degree in genetics to understand. Here, we'll give an overview of DNA and answer questions ...

In bacteria, replication typically initiates from a single replication origin (oriC), which contains several DnaA boxes and the AT-rich DNA unwinding element (DUE). In eukaryotic genomes, replication ...

DNA replication, a central event for cell proliferation, is the basis of biological inheritance. Complete and accurate DNA replication is integral to the maintenance of the genetic integrity of ...

Researchers have gained a clearer insight into how common alterations to the structure of DNA affect the process of DNA replication. These structural changes can put a stop to replication, causing ...