Certain DNA sequences can form structures other than the canonical double helix. These alternative DNA conformations—referred ...

Certain DNA sequences can form structures other than the canonical double helix. These alternative DNA conformations - ...

We employ fully reconstituted yeast and human DNA replication systems to investigate the structure and biochemical mechanism of the eukaryotic replication machinery. A particular focus of the lab is ...

Researchers at the University of Cologne found that mitochondrial dysfunction leads to early skeletal aging by disrupting cartilage metabolism. The study identified maladaptive metabolic shifts, ...

Researchers have uncovered the 3D structure of RBP3, a key protein in vision, revealing how it transports retinoids and fatty ...

A new study from Weill Cornell Medicine provides insights into how cells maintain the tiny end caps of chromosomes as they divide, a key process in ...

New At-Home Laser Device Uses Light-Based Therapy to Help Tackle Stubborn Nail Fungus Without Drugs or Messy Creams. New York ...

Bin Wu, associate professor in the department of Biophysics and Biophysical Chemistry at the School of Medicine, visited ...

NEW YORK – In cell and gene therapies, the genetic machinery is key to producing the proteins missing or dysregulated in a disease, but whether the therapeutic cassette reaches target cells and how ...

An international research team has provided a detailed insight into how the spatial organization of genetic material is established in the cell nucleus of early embryos within the first hours after ...

Knowing how human DNA changes over generations is essential to estimating genetic disease risks and understanding how we ...