Department of Clinical Laboratory Medicine, Southwest Hospital, Third Military Medical University (Army Medical University), 30 Gaotanyan, Shapingba District, Chongqing 400038, China Wageningen Food ...

GSK4418959 (IDE275) induced significant DNA damage selectively in MSI-H cells, but not in MSS cells. DNA damage markers such as gH2AX and pKAP1 were strongly induced both in vitro and in vivo.

Decatur Police said last month they were investigating what caused the damage to the marker but had not determined if it had been damaged intentionally or accidentally. Authorities said on Tuesday ...

The importance of understanding DNA repair Our cells protect their DNA by constantly monitoring and repairing any damage. When DNA is damaged, internal signals activate within the cell to pinpoint ...

We now show that αSyn is preferentially enriched within the nucleolus in melanoma, where it colocalizes with DNA damage markers and DSBs. Inducing DSBs specifically within nucleolar ribosomal DNA ...

Mechanistic studies revealed that wogonin alleviated DNA damage and cardiomyocyte apoptosis by upregulating Sirt1 and downregulating γ-H2AX expression. Docking simulations predicted that wogonin forms ...

Even basic cell division can introduce damage. Repetitive segments can become tangled, and random hits can cause cracks in the DNA structure. Each time a cell copies the DNA blueprint, dozens of ...

Could it be that one of only three known markers directly targeting the DNA does not exist outside the realm of microbes? Now, researchers led by Xiaoqi Feng at the Institute of Science and ...

Could it be that one of only three known markers directly targeting the DNA does not exist outside the realm of microbes? Now, researchers led by Xiaoqi Feng at the Institute of Science and ...

A hallmark of cancer development and progression characterized by the accumulation of DNA damage; genome instability manifests as increased genetic variation across the genome, including ...