b Due to production of non-aldosterone mineralocorticoids ... e Acquired forms due to either licorice ingestion or ectopic ACTH secretion. f Due to increased activity of sodium channels.

6 To confirm the diagnosis of AD, measurements of ACTH, cortisol, plasma renin, and aldosterone are required ... in the diagnosis of AD as cortisol secretion is cyclical, making the results ...

In adrenal insufficiency, a deficiency of cortisol and aldosterone causes chronic fatigue ... from chronic stress or dysregulated melatonin secretion can disrupt circadian rhythms, leading ...

Thiazide diuretics in high doses may worsen glycemic control by impairing insulin secretion and decreasing ... it may be a useful add-on therapy. Aldosterone antagonists (e.g., spironolactone ...

bile secretion, aldosterone regulation of sodium reabsorption, biotin metabolism, steroid hormone biosynthesis, and neuroactive ligand-receptor interactions. Metabolomics and biochemical correlation ...

Further in vivo studies revealed that exosome secretion by glomerular endothelial cells stimulated by high glucose could activate glomerular mesangial cells, leading to mesangial cell proliferation ...

The investigational aldosterone synthase inhibitor lorundrostat effectively lowered 24-hour BP for adults with well-treated, ...

Correspondence to Professor Charalambos Antoniades, Division of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK; antoniad{at}well.ox.ac.uk Adipose tissue (AT ...