In two of the mice, the graft didn’t take. But in the others, the cells switched on a critical beta-cell gene, churned out insulin in response to glucose, and cured the animals.

In type 1 diabetes, beta cells succumb to autoimmunity, leaving individuals with significantly reduced beta-cell mass and a lifelong dependence on insulin replacement therapy.

The lab-grown beta cells produce only 40 percent as much insulin as normal beta cells do, he notes. Therefore, more than 1 billion cells would be needed for a human transplant.

The beta cell whisperer gene Researchers identify a gene that enables beta cells to communicate with each other, helping the pancreas to respond to glucose by insulin secretion Date: November 2, 2022 ...

The promise of beta-cell regeneration — restoring the insulin-producing cells lost in type 1 and type 2 diabetes — has long been considered an ambitious goal. Research now demonstrates that ...

Scientific breakthroughs in one disease don't always shed light on treating other diseases. But that's been the surprising journey of one Mayo Clinic research team. After identifying a sugar molecule ...

Transforming alpha cells into beta cells could be a particularly promising treatment for type 1 diabetes, says Dr. William L. Holland, the senior study author, who is now an assistant professor of ...

Scientists have long suspected that stress hormones help fuel the spread of cancer. Now, new research has uncovered how a ...