More information: p16Ink4a-induced senescence of pancreatic beta cells enhances insulin secretion, Nature Medicine, DOI: 10.1038/nm.4054 ...

The enzyme works to enhance glucose-stimulated insulin secretion from pancreatic beta cells. Insulin helps the body process blood sugar (glucose), and those with type 2 diabetes have a deficiency ...

Blood sugar triggers the secretion of insulin from cells in the pancreas, a process that is impaired in diabetes. A team of Yale researchers have identified a mechanism at the membranes of these ...

The experiments resulted in an increased insulin secretion in the islets of Langerhans of the three donors. The increase was approximately threefold in all the donors.

The 2013 study found that when TMEM24 expression was reduced, insulin secretion was similarly diminished. However, the Yale team wondered whether the lipid-transfer function of the protein was ...

Typically, insulin is secreted by beta-cells in the pancreas in response to glucose—a process that is aptly called glucose-stimulated insulin secretion (GSIS).

Typically, insulin is secreted by cells in the pancreas called ‘beta-cells,’ in response to glucose—a process that is aptly called ‘glucose-stimulated insulin secretion (GSIS).

Figure 1: Signals regulating insulin secretion and the role of SIK2 in this process. (a) Schematic illustration depicting major stimulus–secretion coupling mechanisms in the pancreatic β-cell.

Archive Insulin Secretion in Obesity Authors: Robert A. Kreisberg, M.D., Buris R. Boshell, M.D., John DiPlacido, and Roy F. Roddam, M.D. Author Info & Affiliations Published February 9, 1967 ...

Letter Published: 14 September 1968 New Hypothesis of Insulin Secretion PAUL E. LACY, SIMON L. HOWELL, DONALD A. YOUNG & C. JOAN FINK Nature 219, 1177–1179 (1968) Cite this article ...

Lars Thim, Mogens T. Hansen, Kjeld Norris, Inge Hoegh, Esper Boel, John Forstrom, Gustav Ammerer, Niels P. Fiil, Secretion and Processing of Insulin Precursors in Yeast, Proceedings of the National ...

"Cellular aging process unexpectedly enhances insulin secretion." ScienceDaily. ScienceDaily, 7 March 2016. <www.sciencedaily.com / releases / 2016 / 03 / 160307113948.htm>.