New research reveals how breaking down stored glucose (glycogen) in the brain may reduce toxic protein buildup linked to ...

Because patients with IPF have lung fibrosis, Sun wondered if complex carbohydrate metabolism was also altered in this condition. Using MALDI-MSI, they observed that glycogen- and N-linked glycan-rich ...

Regulation of hepatic glycogen metabolism. Under fasting conditions, glucagon and epinephrine induce cAMP-dependent signaling cascades, leading to the activation of glycogen phosphorylase and ...

Glycogen, a hyperbranched polymer of glucose, plays a central role as an energy reserve across diverse organisms. In Escherichia coli, its biosynthesis is linked not only to energy storage but ...

Details about the role of glycogen turnover and the uncoupling of ATP production in fat cells appeared October 27 in Nature, in an article titled, “ Glycogen metabolism links glucose homeostasis ...

Redirecting metabolism for neuroprotection The authors restored GlyP function in fruit flies and human neurons by either genetic manipulation or chemical stimulation. This intervention did not funnel ...

Brain glycogen serves as a critical glucosamine cache required for protein glycosylation. Cell Metabolism, 2021; DOI: 10.1016/j.cmet.2021.05.003 ...

Glycogen regulates and promotes fat metabolism: the higher the levels, the more robust the metabolic processes, essentially burning fat quicker with resulting weight loss in obese mice.

This study is the first to confirm, in a large-scale prospective cohort, that fish oil supplementation can reduce the risk of developing type 2 diabetes (T2D) in individuals with prediabetes. It ...

Fructose Tolerance: Despite its failure to further augment liver glycogen synthesis, the ingestion of pure fructose resulted in enhanced gastrointestinal (GI) complaints throughout the recovery ...

A surprising discovery about how brain cells handle sugar could shift how scientists approach dementia and Alzheimer’s treatments. In a new study published in Nature Metabolism, researchers ...