It transduces inhibitory signals that down-regulate immune functions induced by activating receptors when co-ligated with the latter receptors. FcγRIII (Fc gamma receptor III, CD16) ...

Fc receptor co-expression and function Immune surveillance is redundant and is reflected by the co-expression of multiple ITAM- or ITIM-containing Fc receptors on the same cell.

Study: An anti-SARS-CoV-2 non-neutralizing antibody with Fc-effector function defines a new NTD epitope and delays neuroinvasion and death in K18-hACE2 mice. Image Credit: ktsdesign / Shutterstock.com ...

Our cover story this month is on the next wave of immune-based therapies for patients with immune-mediated inflammatory conditions — and the prospects are bright.I want to thank our faculty ...

Over the last several decades, antibodies (Abs) have become a valuable weapon in the fight against viral infections, with several studies demonstrating the importance of both neutralizing and ...

SCOTTSDALE, Ariz. — A novel therapeutic approach targeting the neonatal fragment crystallizable receptor may have implications across a number of rheumatology disease states, according to a ...

The Fc gamma receptors play important roles in the initiation and regulation of many immunological and inflammatory processes. They also have the ability to bind RA-associated antibodies.

Christopher L. Haga, Götz R. A. Ehrhardt, Rebecca J. Boohaker, Randall S. Davis, Max D. Cooper, Fc Receptor-Like 5 Inhibits B Cell Activation via SHP-1 Tyrosine Phosphatase Recruitment, Proceedings of ...

In vitro analysis of suicide gene expression and function in human T lymphocytes transduced to express a tumor-targeted chimeric antigen receptor. Background: FCGR3A (CD16) polymorphisms affect the ...