It transduces inhibitory signals that down-regulate immune functions induced by activating receptors when co-ligated with the latter receptors. FcγRIII (Fc gamma receptor III, CD16) ...

Fc receptor co-expression and function Immune surveillance is redundant and is reflected by the co-expression of multiple ITAM- or ITIM-containing Fc receptors on the same cell.

Over the last several decades, antibodies (Abs) have become a valuable weapon in the fight against viral infections, with several studies demonstrating the importance of both neutralizing and ...

Study: An anti-SARS-CoV-2 non-neutralizing antibody with Fc-effector function defines a new NTD epitope and delays neuroinvasion and death in K18-hACE2 mice. Image Credit: ktsdesign / Shutterstock.com ...

Our cover story this month is on the next wave of immune-based therapies for patients with immune-mediated inflammatory conditions — and the prospects are bright.I want to thank our faculty ...

In vitro analysis of suicide gene expression and function in human T lymphocytes transduced to express a tumor-targeted chimeric antigen receptor. Background: FCGR3A (CD16) polymorphisms affect the ...

The Fc gamma receptors play important roles in the initiation and regulation of many immunological and inflammatory processes. They also have the ability to bind RA-associated antibodies.

SCOTTSDALE, Ariz. — A novel therapeutic approach targeting the neonatal fragment crystallizable receptor may have implications across a number of rheumatology disease states, according to a ...

Christopher L. Haga, Götz R. A. Ehrhardt, Rebecca J. Boohaker, Randall S. Davis, Max D. Cooper, Fc Receptor-Like 5 Inhibits B Cell Activation via SHP-1 Tyrosine Phosphatase Recruitment, Proceedings of ...