Here, we define a requirement for neural activity in mobilizing the antioxidant defenses of the nematode Caenorhabditis elegans both during chronic oxidative stress and prior to its onset. We show ...

The brain’s neuromodulatory system produces brain chemicals that impact mood, learning, attention, responsiveness, and memory ...

The cholinergic system is a potent neuromodulatory system which plays a critical role in cortical plasticity, attention and learning. The cholinergic activation of the cortex increases the ...

Three the approved drugs for Alzheimer’s disease attempt to boost the brain’s supply of acetylcholine, a critical neurotransmitter for cognition that wanes in people with the disease. But might ...

Vagus nerve stimulation drives selective circuit modulation through cholinergic reinforcement. Neuron, 2022; DOI: 10.1016/j.neuron.2022.06.017 ...