Ruffin, A. T., et al. (2025) Dysfunctional CD11c − CD2 1− extrafollicular memory B cells are enriched in the periphery and tumors of patients with cancer. Science Translational Medicine. doi ...

A vaccine successfully induced specific B cells in rhesus macaques, paving the way for an effective HIV vaccine in humans.

To better understand T-bet-expressing memory B cells, UAB researchers infected mice with flu virus. Thirty days after infection, they isolated mature memory B cells that were specific for response ...

A measles infection feeds on these memory cells. Vaccines, in contrast, stimulate the production of memory B and T cells without consuming others in the process.

To better understand T-bet-expressing memory B cells, UAB researchers infected mice with flu virus. Thirty days after infection, they isolated mature memory B cells that were specific for response ...

When a booster was given in the same location, these 'primed' macrophages -- already on alert -- efficiently captured the antigen and activated the memory B cells to make high quality antibodies.

MHCII presentation by B cells enables a T cell-dependent response, which provides co-stimulation and cytokine support that drives B cell proliferation, germinal center formation, and isotype switching ...