Sign up for our NewslettersOriginal storyThe Greenville County Sheriff's Office is actively searching for a man with medical ...

A few to scattered evening showers and storms are likely Monday & Tuesday. Numerous showers and storms return to the region ...

Here is a list of free fireworks shows this week in the Upstate area of South Carolina: Fireworks at 9:30 p.m. (If we missed ...

Upstate festivals this summer have something for everyone, from music to plays to food and more. Here's when, where and how ...

Heat index values are expected to reach the upper 90s to around 100 degrees, increasing the risk of heat-related illnesses.

Two youth baseball coaches have been fired after they were filmed stripping naked and streaking at an upstate New York ...

Now, an Upstate doula care service is hosting an event to educate and support mothers to help them know their rights, and ...

Two other upstate waterways, one in Western New York and one in the Adirondacks, also made the list of the nation's best ...

Rochester's Upstate Interiors Academy trains diverse talent for commercial construction jobs, blending trade skills with soft ...

The Pickens County Sheriff’s Office said it is holding a blood drive to help a 14-year-old diagnosed with a rare cancer.

Upstate Medical University is holding a groundbreaking ceremony for a new, state-of-the-art laboratory called the Upstate ...