An often-overlooked mechanism of gene regulation may be involved in the failure of antifungal drugs in the ... used the known mode of action of fluorocytosine on A. fumigatus as the basis for ...

Basilea Pharmaceutica Ltd, Allschwil (SIX: BSLN), a commercial-stage biopharmaceutical company committed to meeting the needs of patients with severe bacterial and fungal infections, announced today ...

"For decades, clinicians have relied on a handful of antifungal classes, with few mechanisms of action and significant limitations due to spectrum of activity, drug toxicities, or drug-drug ...

The development and spread of antibiotic resistance represents one of the greatest threats to global health. To overcome ...

NovaBiotics’ platform technologies leverage defense strategies of the innate immune system and provide first-in-class antibacterial and antifungal ... platforms have mechanisms of action that ...

Writing in Nature, researchers from China Pharmaceutical University and Shandong University have revealed the discovery of a new polyene antifungal antibiotic, mandimycin.

Since mid-2002, two new antifungal drugs — voriconazole ... Both drugs have greater efficacy (because of their specific mechanisms of action), more favourable toxicity profiles and are much ...