Understanding the mechanism of action of an antifungal molecule matters, because it allows scientists to generate related versions to try to improve on nature’s two-billion-year head start.

Basilea Pharmaceutica Ltd, Allschwil (SIX: BSLN), a commercial-stage biopharmaceutical company committed to meeting the needs of patients with severe bacterial and fungal infections, announced today ...

Once considered obscure or opportunistic, invasive fungal infections are now surfacing with alarming frequency - and in ...

An often-overlooked mechanism of gene regulation may be involved in the failure of antifungal drugs in the ... used the known mode of action of fluorocytosine on A. fumigatus as the basis for ...

The development and spread of antibiotic resistance represents one of the greatest threats to global health. To overcome ...

Writing in Nature, researchers from China Pharmaceutical University and Shandong University have revealed the discovery of a new polyene antifungal antibiotic, mandimycin.

"For decades, clinicians have relied on a handful of antifungal classes, with few mechanisms of action and significant limitations due to spectrum of activity, drug toxicities, or drug-drug ...

This mode of action means that it is effective against fungal pathogens that have evolved resistance to existing antifungal agents that target ergosterol, such as the clinically used agent ...