Cleveland Clinic virology researchers have found that a specific protein modification to the immune protein MDA5 is key to how human bodies detect and respond to viruses and viral replication.

Since HIV’s discovery in the 1980s, scientists have come a long way in understanding the different steps required for its assembly ... and what role the lipid envelope plays in HIV replication.

During replication, newly copied viral genomes are packaged up into this ... Viral assembly involves a multi-step process, starting in the cell's nucleus with assembly of capsids, packaging ...

Viral replication and heart inflammation increased ... Gack and Sarkar say their findings could represent the first step to developing a broad-spectrum antiviral. Current research on combating ...

Notably, they demonstrated that interferon-inducible transmembrane proteins inhibit an early step of influenza replication ... of these genes inhibited WSN virus replication in multiple-cycle ...

Viral replication and heart inflammation increased ... Gack and Sarkar say their findings could represent the first step to developing a broad-spectrum antiviral. Current research on combatting ...