USC researchers have developed an innovative type of cancer-fighting immune cell, the EchoBack CAR T-cell, that uses focused ...

The specificity of T cell recognition is determined by the variable (V) domain of the T cell receptor (TCR ... our efforts on solving the crystal structure of a mouse TCR in complex with an ...

To date, the Food and Drug Administration (FDA) has approved seven chimeric antigen receptor-T (CAR-T) cell therapies and seven bispecific T-cell engagers (BiTEs) across a variety of hematologic ...

The CAR T-cell therapy KYV-101 is safe, and showed preliminary signs of efficacy in patients with progressive forms of MS in ...

In part 4 of an interview with The American Journal of Managed Care®, Frederick L. Locke, MD, provides insight on the design ...

A team of researchers has successfully created more effective immune cells that can fight cancer without damaging healthy ...

Chimeric antigen receptor (CAR) T-cell therapy has transformed the treatment of refractory or relapsed leukemia and hematologic malignancies, particularly over the past decade. Despite its ...

Researchers have developed novel lymph-node-inspired hydrogels that significantly enhance the activation, gene expression, ...

CAR-T cells are genetically engineered T-lymphocytes that express a chimeric antigen receptor targeting a specific antigen on cancer cells. In standard CAR-T cell therapy, these T-lymphocytes are ...

A team of researchers from Barcelona has developed a new material that could make one of the most promising cancer treatments ...