The Sodium-Proton Exchange Inhibition to Prevent Coronary Events in Acute Cardiac Conditions (EXPEDITION) trial was designed to investigate whether treatment with the NHE-1 inhibitor, cariporide ...

BOSTON — Fewer patients with pulmonary arterial hypertension died at three time points with use of a sodium-glucose cotransporter-2 inhibitor, according to data presented at the CHEST Annual ...

Combined use of SGLT2 inhibitors and GLP-1 receptor agonists also significantly increased the risk for falls. HealthDay News — Sodium-glucose cotransporter 2 (SGLT2) inhibitor use is an ...

Investigators found that in patients with diabetes and cancer, sodium glucose cotransporter-2 inhibitors were associated with a higher risk of diabetic ketoacidosis and fracture and a lower risk ...

PDF Key points Sodium–glucose cotransporter-2 (SGLT2) inhibitors are an effective treatment for heart failure, chronic kidney disease, and type 2 diabetes, but increase the risk of diabetic ...

Objective Sodium–glucose cotransporter 2 (SGLT-2) inhibitors are the most recently approved antihyperglycemic medications. We sought to describe their association with euglycemic diabetic ...

Using their system, the authors tested a novel therapeutic candidate, in which they showed that the sodium/hydrogen exchange inhibitor EIPA could significantly reduce the mitochondrial responses ...

Asana BioSciences Announces Topical Sodium Channel Blocker ASN008 Achieves Positive Results for the Treatment of Pruritus in Atopic Dermatitis; and Provides Update on JAK/SYK Inhibitor Gusacitinib ...