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RAD51 biomarker could complement next-generation sequencing in personalizing prostate cancer treatmentPatients with RAD51-low scores experienced longer progression free survival (PFS) on treatment with PARP inhibitors or platinum chemotherapy. "Our results demonstrate the feasibility of using the ...
80% presented RAD51 protein levels correlating with functional HRD. The pCR rate in patients treated with the PARP inhibitor who had HRD by RAD51 was 66.7%. This decreased to 22.2% in patients ...
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