Poly adenosine diphosphate-ribose polymerase (PARP) inhibitors, a class of targeted anticancer therapies, prevent genetic ...

OCOG-RATIONAL: A phase II randomized trial of optimal recurrence-directed therapy (RDT) without or with androgen-deprivation therapy (ADT) in radio-recurrent oligo-metastatic castrate sensitive ...

Model of targetable PARPi reversible senescence. The combination of PARPi and a senolytic was effective in preclinical models of ovarian cancer suggesting that coupling these synthetic lethalities ...