The nicotinic acetylcholine receptors (nAChRs ... to be discovered and is one of the most important in the central nervous system (CNS) and peripheral nervous system (PNS). ACh is produced ...

Ines Ibañez-Tallon is revealing how an understudied region of the brain plays an outsized role in opioid and nicotine ...

The Trump administration has proposed terminating a $56 million annual grant program that distributes naloxone, also known by ...

which work by binding to opioid receptors throughout the central nervous system, in both the brain and spinal cord. Finding the right sodium channel target, however, took decades of research ...

the more opioid receptors participants had, the more strongly their brains reacted in MRI scans. “These results show for the first time directly that listening to music activates the brain’s opioid ...

Figure 1: Generation of mice deficient for Gr in the nervous system. Figure 2: Mice lacking Gr in the nervous system display symptoms characteristic of Cushing syndrome including reduced size ...

The U.S. Food and Drug Administration (FDA) has approved a new drug for the treatment of moderate-to-severe pain that is a ...

The mechanism of action of fentanyl is best described by its agonist interaction with the opioid ... receptor. These sites of interaction are primarily distributed throughout the central nervous ...