Ichthyosis vulgaris is a skin condition where the skin’s surface becomes dry, thick, and scaly. Most cases of ichthyosis vulgaris are hereditary and begin in childhood. In rare instances, adults ...

The FDA has granted a breakthrough designation to Timber Pharmaceuticals’ topical isotretinoin formulation for the treatment of congenital ichthyosis, the company announced in a press release.

TMB-001 is an investigational topical reformulation of isotretinoin for the treatment of congenital ichthyosis. The phase 3 program evaluating TMB-001 did not meet primary and secondary endpoints.

Ichthyosis vulgaris is an inherited or acquired skin condition that occurs when the skin doesn’t shed its dead skin cells. This causes dry, dead skin cells to accumulate in patches on the surfac ...