The following is a summary of "ADORA2B promotes proliferation and migration in head and neck squamous cell carcinoma and is ...

Melanoma remains a clinical challenge largely due to its strong immunosuppressive tumor microenvironment, which weakens the effectiveness of conventional immune checkpoint inhibitors ... it activates ...

In patients with bladder cancer, lactylation score may predict survival and efficacy of immune checkpoint inhibitor treatment, according to researchers.

In order to address the challenge of sepsis treatment through immune metabolic modulation, the research team led by Prof.

Removing EPO signaling in mouse liver tumors leads to tumor regression along with sensitivity to immunotherapy.

A hallmark of tumor cells is an inability to control their proliferation, which implies that these cells are capable of bypassing cell cycle checkpoints and regulation by tumor suppressor signaling ...

The protein QRICH1 is a recently identified component of a signaling pathway of CD8 + cells ... Carter et al, QRICH1 mediates an intracellular checkpoint for CD8 + T cell activation via the ...

which has been infiltrated by lymphocytes (red), and is already considered vulnerable to checkpoint inhibitor therapy. Normally, TGF-Beta soothes the immune system, and some cancers use it to evade ...

Development of a new nano-immune agonist to improve immunotherapy for melanoma, a challenging skin cancer, by changing the ...