Agranulocytosis is the most severe adverse effect of antithyroid drug therapy ... were all substantially higher in the group that received 30 mg methimazole per day than in the 15 mg per day ...

With hyperthyroidism (overactive thyroid), two antithyroid drugs are used to tamp down the overproduction of T3 and T4 by the ...

Hyperthyroidism is often treated with antithyroid drugs in pregnancy. However, they are not completely safe to use during pregnancy as methimazole increases risk of neonatal malformations and ...

A declining TRAb concentration during long-term antithyroid drug therapy is suggestive of remission. However TRAb measurements can be misleading in 25% of such patients. TRAb measurements are ...

Mothers with active Graves' disease should be treated with antithyroid drugs, which impact both maternal and fetal thyroid function. Optimally, the lowest possible dose should be used to maintain ...