Levocloperastine with its dual mechanism of action acts on both the central bulbar cough centre and on peripheral receptors in the tracheobronchial tree. In preclinical studies, levocloperastine ...

Rationally designed nanoformulations of conventional chemotherapeutics are able to exert dual mechanisms of action: antiangiogenic effects exerted on the endothelial cells as well as direct ...

“But because MBNL protein expression is regulated by miR-23b, we decided to explore that target as a therapeutic approach and discovered that playing on it leads to a dual mechanism of actio ...

Mounjaro’s dual mechanism of action may provide stronger effects on blood sugar control and weight loss compared to Trulicity, which focuses solely on GLP-1. However, Trulicity has been ...

Scientists at the Terasaki Institute for Biomedical Innovation, in collaboration with the University of Maryland School of ...

Sepiapterin has a dual mechanism of action to increase activity of the phenylalanine hydroxylase enzyme in patients with PKU, a rare, inherited metabolic disease. The new data revealed that over ...

This novel agent has a dual mechanism of action: direct targeting of tumour cells and exertion of immune-cell modulatory effects (Fig. 1). BI 907828 binds directly to MDM2 and blocks its ...