Corticosteroid therapy must be tapered because of its interactions with the hypothalamic-pituitary-adrenocortical (HPA) axis. The hypothalamus secretes corticotropin releasing factor, which acts ...

22% with melphalan and prednisone, 15% with high-dose melphalan, 11% with dexamethasone and lenalidomide, 8% with melphalan, prednisone and bortezomib, and 4% with intermediate-dose melphalan.

G. et al. Bortezomib or high-dose dexamethasone for relapsed multiple myeloma. N. Engl. J. Med. 352, 2487–2498 (2005). Mateos, M. V. et al. Bortezomib plus melphalan and prednisone in elderly ...

The Committee for Medicinal Products for Human Use (CHMP) has recommended that the CD30-directed antibody-drug conjugate (ADC ...

A prednisone taper gradually reduces your corticosteroid dose over days, weeks, or months to prevent prednisone withdrawal. Stopping prednisone abruptly can lead to adrenal insufficiency ...